Schwannoma
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| Schwannoma |
Schwannoma is a benign peripheral nerve
sheath tumor.
Schwannomas are usually solitary.
Cell of origin of Schwannoma -
Differentiated Schwann cells.
Pathologically Schwannomas are unique,
because schwannomas do not infiltrate
the parent nerve.
Surgical significance of this unique
feature is that schwannoma can be enucleated in toto by preserving the adjacent nerve.
 |
| Longitudinal Incision |
 |
| Schawannoma Enucleation |
 |
| Thinned Out Nerve Sheath After Enucleation |
Histological characteristics of schwannoma
– Areas of cellular component (Antoni A) and areas of hypocellular component
(Antoni B).
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Most Important Differential Diagnosis of
schwannoma is Neurofibroma.
Neurofibromas are usually multiple.
Cell of origin of Neurofibroma- Transformed
Schwann cells.
Pathologically neurofibroma infiltrates
the parent nerve.
Surgical significance – Neurofibroma is resected along with the parent nerve and nerve
grafting is done to preserve the nerve function
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Discussion on Neurofibromatosis
Two Types of Neurofibromatosis- Type
1& Type 2
Type 1 Neurofibromatosis is associated
with
Café
au lait patches
Lisch
nodules
Optic
glioma
Type 2 Neurofibromatosis is associated
with
Bilateral
acoustic neuromas
Meningioma
Mesothelioma
Glioma
multiforme
Carcinoma
of Breast
Carcinoma
Colorectum,
Renal
Cell Carcinoma
Hepato
Cellular Carcinoma
Prostatic
Carcinoma
Cutaneous
malignancy
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Image Courtesy- Trivandrum Surgical Club
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